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Zopiclone is a non-benzodiazepine hypnotic medicine, often described as a Z-drug, used for the short-term treatment of insomnia. It may be prescribed when sleep problems are severe and are significantly affecting daily life.
Zopiclone acts on GABA-related receptors in the brain, helping to reduce the time it takes to fall asleep and supporting sleep maintenance through the night.
Because tolerance and dependence can develop, Zopiclone is generally intended for short-term use under appropriate medical supervision.
Zopiclone binds to GABA-A receptor sites in the brain and enhances the calming effect of GABA, an inhibitory neurotransmitter involved in sleep and relaxation.
This can help shorten the time needed to fall asleep, reduce nighttime awakenings and improve overall sleep continuity.
| Property | Detail |
|---|---|
| Active Ingredient | Zopiclone |
| Strength | 7.5mg per tablet |
| Medicine Class | Non-benzodiazepine hypnotic (Z-drug) |
| General Onset | Usually begins working relatively quickly after administration |
| General Duration | Designed to support a normal night's sleep |
| Common Use | Short-term treatment of insomnia |
Zopiclone may be prescribed for short-term sleep problems such as:
Zopiclone is available in different strengths. The appropriate dose depends on factors such as age, medical history, liver or kidney function and other medicines being taken.
| Strength | Information |
|---|---|
| 3.75mg | A lower-strength formulation that may be prescribed when a reduced dose is appropriate. |
| 7.5mg | A commonly available adult strength of Zopiclone. |
Dosage: Take Zopiclone exactly as prescribed by your healthcare professional. It is normally taken immediately before bedtime, and sufficient time should be available for a full night's sleep.
Common side effects of Zopiclone may include:
Important: Zopiclone can cause tolerance, dependence and withdrawal symptoms if used regularly for longer periods. Avoid alcohol while taking it, as alcohol can significantly increase sedation and other adverse effects.
Zopiclone and Temazepam are both medicines that may be used for insomnia, but they belong to different drug classes and have different prescribing considerations.
| Feature | Zopiclone | Temazepam |
|---|---|---|
| Class | Non-benzodiazepine hypnotic (Z-drug) | Benzodiazepine |
| Primary Use | Short-term treatment of insomnia | Short-term treatment of insomnia in certain patients |
| General Action | Enhances GABA-related activity involved in sleep | Enhances GABA activity with sedative effects |
| Dependence | Dependence and tolerance can occur | Dependence and tolerance can occur |
| Selection | The appropriate medicine should be selected by a healthcare professional based on the patient's symptoms, medical history and other medicines. | |
Neither medicine is automatically better for every patient. Treatment depends on the type of insomnia, duration of symptoms, other health conditions and individual response.
Read our full Zopiclone vs Temazepam comparison



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